Endocrine Abstracts

Background: The rapid advancements in the field of allogenic hematopoietic stem cell transplantation (allo-HSCT) and better management of acute postprocedural complications have led to increased life expectancy, but at the same time to higher incidences of long-term complications. Conditioning regimens (chemotherapy, total body irradiation), immunosuppresive treatments and immune dysregulation threaten endocrine and metabolic functions, leading to late effects, including hypog...

Background: Childhood acute lymphoblastic leukemia (ALL) is no longer a death sentence. With survival rates approaching 90%, focus needs to shift towards improving long-term quality of life. Compared to the general population, adult survivors have four-fold excess risk of mortality secondary to cardiovascular diseases. Thus, modifiable risk factors, such as altered glucose metabolism, are of great importance and should be actively sought after. Studies show high prevalences of...